The Biosynthesis of Glycoproteins
نویسندگان
چکیده
منابع مشابه
The Biosynthesis of Glycoproteins
It was previously shown that the particulate fraction of liver was the site of incorporation of glucosamine-l-14C into rat plasma glycoproteins (1). In continuing these studies, we wished to determine whether this incorporation was dependent on the synthesis of protein de nova. Since puromycin inhibits protein biosynthesis (2-5), we have studied the effect of this drug on the incorporation of g...
متن کاملOn the biosynthesis of glycoproteins.
Covalent carbohydrate-protein compounds are wi dely distributed natural products. They are found mainly in animals, vertebrates and invertebrates, but recently their occurrence in green plants has also been reported1. All carbohydrate-protein compounds have the same fundamental structure. Their overall design is that of a polypeptide backbone to which are joined covalently one or more carbohyd...
متن کاملBiosynthesis of Glycoproteins
The presence of carbohydrate in many plasma and tissue proteins is well established (1, 2). The glycoproteins thus far studied contain one or several oligosaccharide units linked to a peptide chain by uncharacterized linkages. Little is yet known about the biosynthetic processes by which the oligosaccharide units are assembled and attached to the polypeptide chain. In order to approach these pr...
متن کاملCell wall O-glycoproteins and N-glycoproteins: aspects of biosynthesis and function
Cell wall O-glycoproteins and N-glycoproteins are two types of glycomolecules whose glycans are structurally complex. They are both assembled and modified within the endomembrane system, i.e., the endoplasmic reticulum (ER) and the Golgi apparatus, before their transport to their final locations within or outside the cell. In contrast to extensins (EXTs), the O-glycan chains of arabinogalactan ...
متن کاملBiosynthesis and expression of zona pellucida glycoproteins in mammals.
The zona pellucida (ZP) is an extracellular matrix surrounding the oocyte and the early embryo that exerts several important functions during fertilization and early embryonic development. The ZP of most mammalian species is composed of three glycoproteins (ZPA, ZPB, ZPC), products of the gene families ZPA, ZPB and ZPC that have been found to be highly homologous within mammalian species. Most ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1964
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)97698-2